Successful pregnancies following hormone replacement therapy in a patient with premature ovarian failure: a case report

Abstract

Premature ovarian failure is a serious life-changing condition that affects young women, remains an enigma and the researcher’s challenge. Spontaneous pregnancy in a patient with POF is uncommon. If fertility is a concern, treatment usually consists of estrogen therapy as hormone replacement and oocyte donation. We report here a case of a 27-year old woman, who was diagnosed to have premature ovarian failure, started ovulating after 26 months of hormone replacement therapy (HRT). She conceived spontaneously and delivered successfully.