Abstract:
Giant Cell Tumours (GCT) of bone account for 5% of all primary bone tumours. Multicentric variety is a rare variant of this condition,
accounting for less than 1% of all cases and can occur as synchronous or metachronous lesions. We report a 22-year-old male patient with
18 months history of painful progressive swellings around the right knee. Radiographs revealed expansile lytic lesions in the distal femur,
proximal tibia and fibula and core needle biopsy was typical of GCT. Biochemical parameters were normal and radiological investigations
did not reveal any metastasis. The patient was treated by above knee amputation due to the extensive nature of the tumours. The excised
tissue from all sites had features of giant cell tumor with no atypia or malignant cells seen. The patient is free from recurrence or metastasis
at three years follow up.
