Abstract:
The objective of the study was to estimate fasting serum magnesium concentration in patients with type 2 DM
and correlating serum magnesium concentration with micro and macro vascular complication of type 2 DM.100 type 2
diabetes mellitus patients admitted in Navodaya Medical Collage Hospital, Raichur over the period of one year between
1stJanuary 2011 to 31st December 2011, were selected for this study. Detailed history, general physical examination,
systemic examination, and various investigations like FBS, PPBS,HbA1C,Blood urea, serum creatinine and urine
examination were carried out. Serum magnesium was estimated by Calmagite dye method. ECG findings were recorded.
Retinopathy was assessed by direct opthalmoscopy. Hypomagnesemia was found in 35 patients. Observations revealed a
significant co-relations between hypomagnesium and diabetic retinopathy (chisquare=9.672,P=0.0019,DF=1)prevalence
of hypomagnesemia in diabetic with complications was significantly higher compared to diabetic with no complications
(47.36%vs18.60%)(chi-square=7.69, P=0.005 DF=1).Higher prevalence of HbA1C >7% (40.30%vs 24.25%)but the
result were not statistically significant for P value <0.05.Prevalence of hypomagnesemia in type 2 diabetic was 35%.
Prevalence of hypomagnesemia was significantly higher in diabetic with microvascular complications compared to
diabetic s with no microvascular complications. Prevalence of hypomagnesium was significantly higher in patients with
retinopathy .Prevalence of hypomagnesemia was higher in patients with FBS>130 and HbA1C >7 .No significant
associations existed between serum magnesium concentrations and other factors like age, sex, durations of diabetes,
mode of treatment,diabetic neuropathy, ischemic heart disease and hypertension.
