Abstract:
Periodontitis is a chronic bacterial infection to gingival tissue leading to
inflammation, degeneration of connective tissue or increased bone turn over. Apart from
clinical examination, analysis of GCF is a good diagnostic tool but, has several limitations.
Components of salivary proteome, enzymes, are gaining importance in clinical diagnosis
because of non-invasive, simple and less demanding procedures.
Aim of our present study is to estimate LDH, AST, ALP and CPK enzymes in
unstimulated saliva for valuing their importance as routine screening tool in diagnosis of
Periodontitis.
In our study we conclude that increased activity of enzymes like LDH, AST, and
ALP in whole unstimulated saliva when compared with normal control provides good
insight of Periodontitis. Estimations are simple, convenient and do not need any expert
examiner, it can be adapted as test for screening Periodontitis in public health.