Browsing by Author "Thamake, Sanjay I."

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Inhibition of triple-negative and Herceptin- resistant breast cancer cell proliferation and migration by Annexin A2 antibodies

Chaudhary, P.; Thamake, Sanjay I.; Shetty, Praveenkumar K.; Vishwanatha, Jamboor K. (Nature Publishing Group, 2014)

Background: Annexin A2 (AnxA2), a calcium-dependent phospholipid binding protein, is abundantly present at the surface of triple-negative and Herceptin-resistant breast cancer cells. Interactions between cell-surface AnxA2 ...
Reciprocal regulation of annexin A2 and EGFR with her-2 in her-2 negative and herceptin-resistant breast cancer

Shetty, Praveenkumar K.; Thamake, Sanjay I.; Biswas, Swati; Johansson, Sonny L.; Vishwanatha, Jamboor K. (PLOS ONE Publishes, 2012-09-05)

Alternative survival pathways are commonly seen to be upregulated upon inhibition of receptor tyrosine kinases (RTK), including Her-2. It is established that treatment with Herceptin leads to selective overexpression and ...

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